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Test Code 5422615 NRAS MUTATION ANALYSIS

Test ID

1236000031

Specimen Requirements

Collection Requirements

Acceptable Specimen Type: Formalin fixed paraffin tissue on slides, FNA, Solid Tissue

Formalin-fixed paraffin-embedded (FFPE) unstained slides: 10 unstained sections, each 10-microns thick, total >100 mcg tumor; corresponding H&E stained 5-micron section REQUIRED; FNA cell blocks should have >50% tumor cells.

FNA specimens: unrefrigerated fresh neat or in saline or RPMI. Fresh specimens must be received in lab within 3 hours of collection. Refrigerated (not frozen) samples must be received in lab within 24 hours of collection. At least 100,000 tumor cells are required. Tumor cells must be >50% of specimen as predetermined by referring

cytopathologist.

Solid Tissue, fresh or frozen: >500 mcg tumor. Tumor must constitute >50% of specimen as predetermined by referring pathologist. Collect in RPMI, saline, or neat. Fresh specimens must be received in lab within 3 hours of collection. Frozen specimens must be received in lab within 72 hours of collection, ship on dry ice.

Shipping / Handling Instructions

Transport Container

N/A

Transport Temperature

Formalin-fixed paraffin-embedded (FFPE) unstained slides: specimen send room temperature with corresponding pathologist's report

FNA specimens: fresh specimens sent at room temperature must be in lab within 3 hours of collection. Sent refrigerated must be received in lab within 24 hours of collection.

Solid Tissue, fresh or frozen: fresh specimen sent at room temperature must be in lab within 3 hours of collection. Frozen specimens must be received in lab within 72 hours of collection, ship on dry ice.

Specimen Stability

N/A

Rejection Criteria

 

1.) Mercury-based fixative (B-5) FFPE specimens.

2.) Unstained FFPE sections without corresponding H&E section.

3.) FFPE with low % tumor cells.

4.)Decalcified bone tissue.

 

 

 

Container Type

Laboratory

Container

Default

Temperature

Minimum Volume

BIOCENTER LAB

AP SLIDES

STERILE CONTAINER

 

Yes

 

 

 

 

 

 

Performing Section

BIOCENTER LAB: MOLECULAR DIAGNOSTICS

Components

Component Name

Component ID

LOINC Code

MOLDX_N-RAS_RES

N-RAS MUTATION INTERPRETATION

N-RAS MUTATION DISCLAIMER

MOLDX N-RAS MUTATION SIGNATURE 

1238000315

1230002647

12300002416

12300002472

21720-8