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HelpTest Code CTX Beta-CrossLaps, Serum
Reporting Name
Beta-CrossLaps (B-CTx), SUseful For
Monitoring antiresorptive therapies (eg, bisphosphonates and hormone replacement therapy) in postmenopausal women treated for osteoporosis and individuals diagnosed with osteopenia
An adjunct in the diagnosis of medical conditions associated with increased bone turnover
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Patient Preparation:
1. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
2. Patient should be fasting.
Supplies: Aliquot Tube, 5 mL (T465)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial, 5 mL
Specimen Volume: 1 mL
Collection Instructions:
1. Collect specimen prior to 10 a.m.
2. Centrifuge and aliquot serum into plastic vial.
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 90 days | |
| Refrigerated | 72 hours |
Reference Values
Males
<5 years: 242-1292 pg/mL
5-9 years: 351-1532 pg/mL
10-15 years: 447-2457 pg/mL
16-17 years: 478-1666 pg/mL
18-30 years: 120-946 pg/mL
31-50 years: 93-630 pg/mL
51-70 years: 35-836 pg/mL
>70 years: not established
Females
<5 years: 347-1508 pg/mL
5-9 years: 383-1556 pg/mL
10-15 years: 311-1776 pg/mL
16-17 years: 146-1266 pg/mL
Premenopausal: 25-573 pg/mL
Postmenopausal: 104-1008 pg/mL
Day(s) and Time(s) Performed
Monday through Friday; 5 a.m.-12 a.m.
Saturday; 6 a.m.-6 p.m.
Test Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82523
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CTX | Beta-CrossLaps (B-CTx), S | 41171-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CTX | Beta-CrossLaps (B-CTx), S | 41171-0 |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Method Name
Electrochemiluminescence Immunoassay (ECLIA)