Test Code HIAA 5-Hydroxyindoleacetic Acid, 24 Hour, Urine
Reporting Name
5-Hydroxyindoleacetic Acid, UUseful For
Biochemical diagnosis and monitoring of intestinal carcinoid syndrome
Performing Laboratory

Specimen Type
UrineNecessary Information
24-hour volume is required.
Specimen Required
Patient Preparation:
1. Some medications could interfere with test results. The ordering provider should decide if any medications should be stopped and when they should be restarted. If clinically feasible, discontinue the following medications at least 48 hours prior to, as well as during, specimen collection:
-Acetaminophen (Tylenol or generic versions)
-Aspirin
-Antihistamines
-Cough syrups
-Cold and flu medications
2. For 48 hours prior to, as well as during, the urine collection, the patient should:
Limit the following to 1 serving per day:
-Fruits
-Vegetables
-Nuts
-Caffeinated beverages or foods
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a 24-hour urine specimen.
2. Add 25 mL of 50% acetic acid as preservative at start of collection. Use 15 mL of 50% acetic acid for children <5 years old.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 56 days | |
Frozen | 365 days |
Special Instructions
Reference Values
5HIAA, mg/24 hour 99th percentile cutoff |
||
Age |
Female |
Male |
≤23 months |
≤2.7 |
≤2.3 |
24-35 months |
≤3.0 |
≤2.6 |
3 years |
≤3.2 |
≤2.9 |
4 years |
≤3.4 |
≤3.2 |
5 years |
≤3.6 |
≤3.6 |
6 years |
≤3.8 |
≤3.9 |
7 years |
≤4.0 |
≤4.2 |
8 years |
≤4.2 |
≤4.5 |
9 years |
≤4.5 |
≤4.8 |
10 years |
≤4.7 |
≤5.1 |
11 years |
≤4.9 |
≤5.3 |
12 years |
≤5.2 |
≤5.6 |
13 years |
≤5.4 |
≤5.8 |
14 years |
≤5.6 |
≤6.1 |
15 years |
≤5.7 |
≤6.3 |
16 years |
≤5.9 |
≤6.4 |
17 years |
≤6.0 |
≤6.6 |
18 years |
≤6.0 |
≤6.7 |
19 years |
≤6.1 |
≤6.8 |
20 years |
≤6.1 |
≤6.9 |
21 years |
≤6.2 |
≤6.9 |
22 years |
≤6.2 |
≤7.0 |
23 years |
≤6.2 |
≤7.0 |
24 years |
≤6.3 |
≤7.1 |
25 years |
≤6.3 |
≤7.2 |
26 years |
≤6.3 |
≤7.2 |
27 years |
≤6.4 |
≤7.3 |
28 years |
≤6.4 |
≤7.4 |
29 years |
≤6.5 |
≤7.5 |
30 years |
≤6.6 |
≤7.5 |
31 years |
≤6.6 |
≤7.6 |
32 years |
≤6.7 |
≤7.7 |
33 years |
≤6.8 |
≤7.7 |
34 years |
≤6.8 |
≤7.8 |
35 years |
≤6.9 |
≤7.9 |
36 years |
≤6.9 |
≤7.9 |
37 years |
≤7.0 |
≤8.0 |
38 years |
≤7.0 |
≤8.1 |
39 years |
≤7.0 |
≤8.2 |
40 years |
≤7.1 |
≤8.2 |
41 years |
≤7.1 |
≤8.3 |
42 years |
≤7.2 |
≤8.4 |
43 years |
≤7.3 |
≤8.5 |
44 years |
≤7.4 |
≤8.6 |
45 years |
≤7.4 |
≤8.7 |
46 years |
≤7.5 |
≤8.8 |
47 years |
≤7.6 |
≤8.9 |
48 years |
≤7.6 |
≤9.0 |
49 years |
≤7.7 |
≤9.1 |
50 years |
≤7.7 |
≤9.2 |
51 years |
≤7.8 |
≤9.3 |
52 years |
≤7.8 |
≤9.4 |
53 years |
≤7.9 |
≤9.5 |
54 years |
≤8.0 |
≤9.6 |
55 years |
≤8.1 |
≤9.7 |
56 years |
≤8.1 |
≤9.7 |
57 years |
≤8.2 |
≤9.8 |
58 years |
≤8.3 |
≤9.8 |
59 years |
≤8.3 |
≤9.8 |
60 years |
≤8.3 |
≤9.9 |
61 years |
≤8.3 |
≤9.9 |
62 years |
≤8.4 |
≤9.9 |
63 years |
≤8.4 |
≤10.0 |
64 years |
≤8.4 |
≤10.0 |
65 years |
≤8.4 |
≤10.0 |
66 years |
≤8.5 |
≤10.1 |
67 years |
≤8.5 |
≤10.1 |
68 years |
≤8.5 |
≤10.1 |
69 years |
≤8.5 |
≤10.2 |
70 years |
≤8.5 |
≤10.2 |
71 years |
≤8.6 |
≤10.2 |
72 years |
≤8.6 |
≤10.2 |
73 years |
≤8.5 |
≤10.1 |
74 years |
≤8.5 |
≤10.1 |
75 years |
≤8.6 |
≤10.1 |
76 years |
≤8.6 |
≤10.0 |
77 years |
≤8.6 |
≤10.0 |
78 years |
≤8.6 |
≤10.0 |
79 years |
≤8.6 |
≤10.0 |
80 years |
≤8.7 |
≤9.9 |
81 years |
≤8.7 |
≤9.9 |
82 years |
≤8.7 |
≤9.9 |
83 years |
≤8.7 |
≤9.9 |
84 years |
≤8.7 |
≤9.9 |
85 years |
≤8.6 |
≤9.8 |
86 years |
≤8.5 |
≤9.8 |
87 years |
≤8.4 |
≤9.7 |
88 years |
≤8.3 |
≤9.7 |
89 years |
≤8.1 |
≤9.5 |
90 years |
≤7.9 |
≤9.4 |
91 years |
≤7.6 |
≤9.2 |
92 years |
≤7.4 |
≤9.0 |
93 years |
≤7.1 |
≤8.8 |
94 years |
≤7.0 |
≤8.7 |
= 95 years |
≤6.9 |
≤8.6 |
For SI unit Reference Values, see https://www.mayocliniclabs.com/order-tests/si-unit-conversion.html
Day(s) and Time(s) Performed
Monday through Thursday; 11 a.m.
Friday; 2 p.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83497
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HIAA | 5-Hydroxyindoleacetic Acid, U | 1695-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
9248 | 5-Hydroxyindoleacetic Acid, U | 1695-6 |
TM35 | Collection Duration | 13362-9 |
VL33 | Urine Volume | 3167-4 |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |