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HelpTest Code LAMO Lamotrigine, Serum
Reporting Name
Lamotrigine, SUseful For
Monitoring serum concentration of lamotrigine
Assessing compliance
Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs which interact pharmacokinetically with lamotrigine
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Draw blood immediately before next scheduled dose.
2. For sustained-release formulations ONLY, draw blood a minimum of 12 hours after last dose.
3. Spin down within 2 hours of draw.
4. Remove serum from serum gel tube if applicable.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reference Values
Patients receiving therapeutic doses usually have lamotrigine concentrations of 2.5-15.0 mcg/mL.
Day(s) and Time(s) Performed
Monday through Friday; Continuous until 2 p.m.
Saturday; Continuous until 1 p.m.
Sunday; 11 a.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80175
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LAMO | Lamotrigine, S | 6948-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80999 | Lamotrigine, S | 6948-4 |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Neurology Specialty Testing Client Test Request (T732)
-General Request (T239)
-Therapeutics Test Request (T831)