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HelpTest Code NSE Neuron-Specific Enolase (NSE), Serum
Reporting Name
Neuron Specific Enolase, SUseful For
A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type
An auxiliary test in the diagnosis of small cell lung carcinoma
An auxiliary test in the diagnosis of carcinoids, islet cell tumors and neuroblastomas
An auxiliary tool in the assessment of comatose patients
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic screw-top aliquot tube
Specimen Volume: 0.5 mL
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Ambient | 7 days |
Reference Values
≤15 ng/mL
Serum markers are not specific for malignancy, and values may vary by method.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NSE | Neuron Specific Enolase, S | 15060-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| NSE | Neuron Specific Enolase, S | 15060-7 |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
Day(s) and Time(s) Performed
Monday through Friday; 8 a.m.-2 p.m.
Saturday; 8 a.m.-1 p.m.
Method Name
Homogeneous Time-Resolved Fluorescence
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.