Ordering Guidance

This test will report as negative or positive for autoantibodies to phospholipase A2 receptor (PLA2R).

If additional interpretation/analysis is needed, request PATHC / Pathology Consultation along with this test and send the corresponding renal pathology light microscopy and immunofluorescence (IF) slides (or IF images on a CD), electron microscopy images (prints or CD), and the pathology report.

Shipping Instructions

1. Advise shipping unstained slides or tissue block specimens frozen in Styrofoam transportation coolers filled with dry ice to ensure specimens are received at required specimen stability temperature.

2. Attach the green pathology address label included in the kit to the outside of the transport container.

Necessary Information

A pathology/diagnostic report is required.

Specimen Required

Specimen Type: Kidney tissue

Preferred: Frozen unstained slides (unfixed)

Slides: 2 frozen tissue unstained positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick, centered on the slide, and submitted on dry ice.

Acceptable: Frozen Unfixed Tissue Block (OCT)

Container/Tube: Entire specimen

Collection Instructions: Send tissue embedded in OCT on dry ice.

Acceptable: Wet Tissue

Supplies: Renal Biopsy Kit (T231)

Container/Tube: Renal Biopsy Kit, Zeus/Michel's

Specimen Volume: Entire specimen

Collection Instructions: Collect specimens according to the instructions in Renal Biopsy Procedure for Handling Tissue for Light Microscopy, Immunofluorescent Histology, and Electron Microscopy.

Additional Information: If standard immunoglobulin and complement immunofluorescence have already been performed, submit the residual frozen tissue (must contain glomeruli) on dry ice.