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Test Code SDEX Sickle Solubility, Blood

Reporting Name

Sickle Solubility, B

Useful For

Screening for presence or absence of hemoglobin (Hb) S (sickle cell disease)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole Blood EDTA

Ordering Guidance

This is a screening test only. For quantification of hemoglobin S, order HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood.

Necessary Information

1. Patient's age is required.

2. Include recent transfusion information.

Specimen Required


Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD solution B), green top (heparin)

Specimen Volume: 1 mL

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated 14 days

Reference Values


Day(s) Performed

Monday through Saturday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
SDEX Sickle Solubility, B 6864-3


Result ID Test Result Name Result LOINC Value
9180 Sickle Solubility, B 6864-3

Report Available

1 to 4 days

Reject Due To

Gross hemolysis Reject

Method Name

Hemoglobin S Solubility


If not ordering electronically, complete, print, and send a Benign Hematology Test Request Form (T755) with the specimen.