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HelpTest Code TTST Testosterone, Total, Mass Spectrometry, Serum
Reporting Name
Testosterone, Total, SUseful For
Evaluation of men with symptoms or signs of possible hypogonadism, such as loss of libido, erectile dysfunction, gynecomastia, osteoporosis, or infertility
Evaluation of boys with delayed or precocious puberty
Monitoring testosterone replacement therapy
Monitoring antiandrogen therapy (eg, used in prostate cancer, precocious puberty, treatment of idiopathic hirsutism, male-to-female transgender disorders, etc.)
Evaluation of women with hirsutism, virilization, and oligoamenorrhea
Evaluation of women with symptoms or signs of possible testosterone deficiency
Evaluation of infants with ambiguous genitalia or virilization
Diagnosis of androgen-secreting tumors
Testing Algorithm
See Steroid Pathways in Special Instructions
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum RedNecessary Information
Patient's age and sex are required.
Specimen Required
Container/Tube: Red top (serum gel/SST are not acceptable)
Specimen Volume: 1 mL
Specimen Minimum Volume
0.215 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days | |
| Frozen | 60 days |
Special Instructions
Reference Values
Males
0-5 months: 75-400 ng/dL
6 months-9 years: <7-20 ng/dL
10-11 years: <7-130 ng/dL
12-13 years: <7-800 ng/dL
14 years: <7-1,200 ng/dL
15-16 years: 100-1,200 ng/dL
17-18 years: 300-1,200 ng/dL
≥19 years: 240-950 ng/dL
Tanner Stages*
I (prepubertal): <7-20
II: 8-66
III: 26-800
IV: 85-1,200
V (young adult): 300-950
Females
0-5 months: 20-80 ng/dL
6 months-9 years: <7-20 ng/dL
10-11 years: <7-44 ng/dL
12-16 years: <7-75 ng/dL
17-18 years: 20-75 ng/dL
≥19 years: 8-60 ng/dL
Tanner Stages*
I (prepubertal): <7-20
II: <7-47
III: 17-75
IV: 20-75
V (young adult): 12-60
*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±2) years and for girls at a median age of 10.5 (±2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (young adult) should be reached by age 18.
Day(s) and Time(s) Performed
Monday through Saturday; Continuously until 2 p.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TTST | Testosterone, Total, S | 2986-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8533 | Testosterone, Total, S | 2986-8 |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Portions of this test are covered by patents held by Quest Diagnostics
CPT Code Information
84403
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.